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Antibody class: IgG1κ
ARP-522 is a monoclonal antibody to HIV-1 LAV and IIIB gp120.
This antibody was purified from hybridoma supernatant by protein A affinity chromatography. The hybridoma was generated by immunizing [B10.A (2R) x A.BY] F1 mice with vaccinia virus expressing HIV gp160 and fusing the resulting splenocytes with NS1 cells.
Please see the LANL HIV Molecular Database for more information. This antibody neutralizes infectivity and reacts with cells expressing the envelope proteins of HIV-1 LAV and IIIB strains. It binds to the immunodominant hypervariable loop of gp120 (unpublished results). It does not recognize other HIV-1 strains. The hybridoma used to produce this antibody, Anti-HIV-1 gp120 Hybridoma (902), is available to order. (See cat#: ARP-521)
Note: The user should determine the optimal concentration for any application.
Each vial of ARP-522 contains 500 µg of lyophilized purified antibody.
Note: Avoid freeze-thaw cycles as reagent degradation may result.
Please refer to the attached file(s) for more information
When applying for permits and forms please:
Do NOT reference NIH HIV Reagent Program or ATCC Catalog Numbers in the Material Description
fields found on the permits and/or forms.
Make sure your name and address on the permit applications and/or forms are exactly
as they appear on your NIH HIV Reagent Program registration.
Information about permits is provided as a courtesy to NIH HIV Reagent Program customers.
While we use reasonable efforts to include accurate and up-to-date information on
this page, we make no warranties or representation as to its accuracy.
For more information on the necessary compliance requirements associated with the
biological materials provided by NIH HIV Reagent Program, please select this link: Compliance Requirements.
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